Publication list, Annex Concept – project RHU PERTINENCE

Abadi, A., J. Peralta-Romero, et al. (2016). « Assessing the effects of 35 European-derived BMI-associated SNPs in Mexican children. » Obesity (Silver Spring) 24(9): 1989-1995.

Ahrens, M., O. Ammerpohl, et al. (2013). « DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery. » Cell Metab 18(2): 296-302.

Anand, S. S., D. Meyre, et al. (2013). « Genetic information and the prediction of incident type 2 diabetes in a high-risk multiethnic population: the EpiDREAM genetic study. » Diabetes Care 36(9): 2836-2842.

Andreasen, C. H., K. L. Stender-Petersen, et al. (2008). « Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation. » Diabetes 57(1): 95-101.

Antoine, D., R. M. Guéant-Rodriguez, et al. (2021). « Rare coding variants associated with body-mass-index impact outcomes of bariatric surgery in patients with morbid obesity. » J Clin Endocrinol Metab in revision.

Antoine, D., Z. Li, et al. (2021). « Medium term post-bariatric surgery deficit of vitamin B12 is predicted by deficit at time of surgery. » Clin Nutr 40(1): 87-93.

Aslan, I. R., S. A. Ranadive, et al. (2011). « Bariatric surgery in a patient with complete MC4R deficiency. » Int J Obes (Lond) 35(3): 457-461.

Battaglia-Hsu, S. F., R. Ghemrawi, et al. (2018). « Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR. » Nucleic Acids Res 46(15): 7844-7857.

Beck, B., C. Bossenmeyer-Pourie, et al. (2012). « Increased homocysteinemia is associated with beneficial effects on body weight after long-term high-protein, low-fat diet in rats. » Nutrition 28(9): 932-936.

Bell, C. G., S. Finer, et al. (2010). « Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus. » PLoS One 5(11): e14040.

Bennasroune, A., B. Romier-Crouzet, et al. (2019). « Elastic fibers and elastin receptor complex: Neuraminidase-1 takes the center stage. » Matrix Biol 84: 57-67.

Benzinou, M., J. W. Creemers, et al. (2008). « Common nonsynonymous variants in PCSK1 confer risk of obesity. » Nat Genet 40(8): 943-945.

Berndt, S. I., S. Gustafsson, et al. (2013). « Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. » Nat Genet 45(5): 501-512.

Blaise, S., B. Romier, et al. (2013). « Elastin-derived peptides are new regulators of insulin resistance development in mice. » Diabetes 62(11): 3807-3816.

Bonam, S. R., F. Wang, et al. (2019). « Lysosomes as a therapeutic target. » Nat Rev Drug Discov 18(12): 923-948.

Bonnefond, A., R. Keller, et al. (2016). « Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (MC4R) Gene, and Outcomes of Bariatric Operations: A 6-Year Prospective Study. » Diabetes Care 39(8): 1384-1392.

Bonnefond, A., R. Keller, et al. (2016). « Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (MC4R) Gene, and Outcomes of Bariatric Operations: A Six-Year Prospective Study. » Diabetes Care.

Bonnefond, A., A. Raimondo, et al. (2013). « Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features. » J Clin Invest 123(7): 3037-3041.

Bouatia-Naji, N., D. Meyre, et al. (2006). « ACDC/adiponectin polymorphisms are associated with severe childhood and adult obesity. » Diabetes 55(2): 545-550.

Boyle, E. A., Y. I. Li, et al. (2017). « An Expanded View of Complex Traits: From Polygenic to Omnigenic. » Cell 169(7): 1177-1186.

Bradfield, J. P., H. R. Taal, et al. (2012). « A genome-wide association meta-analysis identifies new childhood obesity loci. » Nat Genet 44(5): 526-531.

Bradfield, J. P., S. Vogelezang, et al. (2019). « A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity. » Hum Mol Genet 28(19): 3327-3338.

Brandt, S., J. von Schnurbein, et al. (2020). « Methylphenidate in children with monogenic obesity due to LEPR or MC4R deficiency improves feeling of satiety and reduces BMI-SDS-A case series. » Pediatr Obes 15(1): e12577.

Buxton, J. L., R. G. Walters, et al. (2011). « Childhood obesity is associated with shorter leukocyte telomere length. » J Clin Endocrinol Metab 96(5): 1500-1505.

Cauchi, S., D. Meyre, et al. (2008). « Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value. » PLoS One 3(5): e2031.

Cauchi, S., F. Stutzmann, et al. (2009). « Combined effects of MC4R and FTO common genetic variants on obesity in European general populations. » J Mol Med (Berl) 87(5): 537-546.

Chami, N., M. Preuss, et al. (2020). « The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population. » PLoS Med 17(7): e1003196.

Chen, S. and D. Meyre (2020). « An update on Mendelian forms of obesity and their personalized treatments. » Obesity and Diabetes Scientific Advances and Best Practice Second Edition Springer: 207-212.

Chiorean, A., W. S. Garver, et al. (2020). « Signatures of natural selection and ethnic-specific prevalence of NPC1 pathogenic mutations contributing to obesity and Niemann-Pick disease type C1. » Sci Rep 10(1): 18787.

Collet, T. H., B. Dubern, et al. (2017). « Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency. » Mol Metab 6(10): 1321-1329.

Creemers, J. W., H. Choquet, et al. (2012). « Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity. » Diabetes 61(2): 383-390.

Croft, J. B., D. Morrell, et al. (1995). « Obesity in heterozygous carriers of the gene for the Bardet-Biedl syndrome. » Am J Med Genet 55(1): 12-15.

Dastani, Z., M. F. Hivert, et al. (2012). « Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. » PLoS Genet 8(3): e1002607.

Dempfle, A., A. Hinney, et al. (2004). « Large quantitative effect of melanocortin-4 receptor gene mutations on body mass index. » J Med Genet 41(10): 795-800.

den Hollander, W. J., L. Broer, et al. (2017). « Helicobacter pylori colonization and obesity – a Mendelian randomization study. » Sci Rep 7(1): 14467.

Dick, K. J., C. P. Nelson, et al. (2014). « DNA methylation and body-mass index: a genome-wide analysis. » Lancet 383(9933): 1990-1998.

Dina, C., D. Meyre, et al. (2007). « Variation in FTO contributes to childhood obesity and severe adult obesity. » Nat Genet 39(6): 724-726.

Doche, M. E., E. G. Bochukova, et al. (2012). « Human SH2B1 mutations are associated with maladaptive behaviors and obesity. » J Clin Invest 122(12): 4732-4736.

Duncan, L., H. Shen, et al. (2019). « Analysis of polygenic risk score usage and performance in diverse human populations. » Nat Commun 10(1): 3328.

Ehtesham, S., A. Qasim, et al. (2019). « Loss-of-function mutations in the melanocortin-3 receptor gene confer risk for human obesity: A systematic review and meta-analysis. » Obes Rev 20(8): 1085-1092.

Farooqi, I. S., J. M. Keogh, et al. (2003). « Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. » N Engl J Med 348(12): 1085-1095.

Frayling, T. M., N. J. Timpson, et al. (2007). « A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. » Science 316(5826): 889-894.

Garcia, M. M., R. M. Gueant-Rodriguez, et al. (2011). « Methyl donor deficiency induces cardiomyopathy through altered methylation/acetylation of PGC-1alpha by PRMT1 and SIRT1. » J Pathol 225(3): 324-335.

Gorisse, L., C. Pietrement, et al. (2016). « Protein carbamylation is a hallmark of aging. » Proc Natl Acad Sci U S A 113(5): 1191-1196.

Gueant, J. L., C. Chery, et al. (2018). « APRDX1 mutant allele causes a MMACHC secondary epimutation in cblC patients. » Nat Commun 9(1): 67.

Gueant, J. L., F. Namour, et al. (2013). « Folate and fetal programming: a play in epigenomics? » Trends Endocrinol Metab 24(6): 279-289.

Hardy, T., M. Zeybel, et al. (2017). « Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease. » Gut 66(7): 1321-1328.

Hatoum, I. J., D. M. Greenawalt, et al. (2013). « Weight loss after gastric bypass is associated with a variant at 15q26.1. » Am J Hum Genet 92(5): 827-834.

He, J., C. Stryjecki, et al. (2019). « Adiponectin is associated with cardio-metabolic traits in Mexican children. » Sci Rep 9(1): 3084.

Hoggart, C. J., G. Venturini, et al. (2014). « Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. » PLoS Genet 10(7): e1004508.

Ichimura, A., A. Hirasawa, et al. (2012). « Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. » Nature 483(7389): 350-354.

Iepsen, E. W., J. Zhang, et al. (2018). « Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist. » Cell Metab 28(1): 23-32 e23.

Jiao, H., P. Arner, et al. (2011). « Genome wide association study identifies KCNMA1 contributing to human obesity. » BMC Med Genomics 4: 51.

Johnson, R. J., T. Nakagawa, et al. (2013). « Sugar, uric acid, and the etiology of diabetes and obesity. » Diabetes 62(10): 3307-3315.

Kaur, Y., D. X. Wang, et al. (2019). « Comprehensive identification of pleiotropic loci for body fat distribution using the NHGRI-EBI Catalog of published genome-wide association studies. » Obes Rev 20(3): 385-406.

Kawecki, C., O. Bocquet, et al. (2019). « Identification of CD36 as a new interaction partner of membrane NEU1: potential implication in the pro-atherogenic effects of the elastin receptor complex. » Cell Mol Life Sci 76(4): 791-807.

Keramati, A. R., M. Fathzadeh, et al. (2014). « A form of the metabolic syndrome associated with mutations in DYRK1B. » N Engl J Med 370(20): 1909-1919.

Khera, A. V., M. Chaffin, et al. (2018). « Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. » Nat Genet 50(9): 1219-1224.

Khera, A. V., M. Chaffin, et al. (2019). « Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood. » Cell 177(3): 587-596 e589.

Kilpelainen, T. O., L. Qi, et al. (2011). « Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. » PLoS Med 8(11): e1001116.

Kohlsdorf, K., A. Nunziata, et al. (2018). « Early childhood BMI trajectories in monogenic obesity due to leptin, leptin receptor, and melanocortin 4 receptor deficiency. » Int J Obes (Lond) 42(9): 1602-1609.

Kokten, T., S. Gibot, et al. (2018). « TREM-1 Inhibition Restores Impaired Autophagy Activity and Reduces Colitis in Mice. » J Crohns Colitis 12(2): 230-244.

Kuehnen, P., M. Mischke, et al. (2012). « An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity. » PLoS Genet 8(3): e1002543.

Kuhnen, P., D. Handke, et al. (2016). « Interindividual Variation in DNA Methylation at a Putative POMC Metastable Epiallele Is Associated with Obesity. » Cell Metab 24(3): 502-509.

Lafarge, J. C., M. Pini, et al. (2014). « Cathepsin S inhibition lowers blood glucose levels in mice. » Diabetologia 57(8): 1674-1683.

Lee, Y. S., B. G. Challis, et al. (2006). « A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance. » Cell Metab 3(2): 135-140.

Li, A., S. Robiou-du-Pont, et al. (2018). « Parental and child genetic contributions to obesity traits in early life based on 83 loci validated in adults: the FAMILY study. » Pediatr Obes 13(3): 133-140.

Li, A., K. K. Teo, et al. (2017). « A genetic link between prepregnancy body mass index, postpartum weight retention, and offspring weight in early childhood. » Obesity (Silver Spring) 25(1): 236-243.

Li, Z., R. M. Gueant-Rodriguez, et al. (2018). « Folate and vitamin B12 status is associated with insulin resistance and metabolic syndrome in morbid obesity. » Clin Nutr 37(5): 1700-1706.

Liu, H. Y., A. Alyass, et al. (2019). « Fine-mapping of 98 obesity loci in Mexican children. » Int J Obes (Lond) 43(1): 23-32.

Liu, R., Y. Zou, et al. (2017). « Rare Loss-of-Function Variants in NPC1 Predispose to Human Obesity. » Diabetes 66(4): 935-947.

Liu, Y. J., X. G. Liu, et al. (2008). « Genome-wide association scans identified CTNNBL1 as a novel gene for obesity. » Hum Mol Genet 17(12): 1803-1813.

Loos, R. J., C. M. Lindgren, et al. (2008). « Common variants near MC4R are associated with fat mass, weight and risk of obesity. » Nat Genet 40(6): 768-775.

Macri, C., F. Wang, et al. (2015). « Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide. » Autophagy 11(3): 472-486.

Manolio, T. A., F. S. Collins, et al. (2009). « Finding the missing heritability of complex diseases. » Nature 461(7265): 747-753.

Mansuy-Aubert, V., Q. L. Zhou, et al. (2013). « Imbalance between neutrophil elastase and its inhibitor alpha1-antitrypsin in obesity alters insulin sensitivity, inflammation, and energy expenditure. » Cell Metab 17(4): 534-548.

Marenne, G., A. E. Hendricks, et al. (2020). « Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription. » Cell Metab 31(6): 1107-1119 e1112.

Melhem, H., F. Hansmannel, et al. (2016). « Methyl-deficient diet promotes colitis and SIRT1-mediated endoplasmic reticulum stress. » Gut 65(4): 595-606.

Mente, A., D. Meyre, et al. (2013). « Causal relationship between adiponectin and metabolic traits: a Mendelian randomization study in a multiethnic population. » PLoS One 8(6): e66808.

Meyre, D., N. Bouatia-Naji, et al. (2005). « Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes. » Nat Genet 37(8): 863-867.

Meyre, D., J. Delplanque, et al. (2009). « Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. » Nat Genet 41(2): 157-159.

Meyre, D., P. Froguel, et al. (2014). « Comment on: Valette et al. Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery. PLOS ONE 2012; 7(11):E48221. » PLoS One 9(3): e93324.

Meyre, D., S. Mohamed, et al. (2019). « Association between impulsivity traits and body mass index at the observational and genetic epidemiology level. » Sci Rep 9(1): 17583.

Minster, R. L., N. L. Hawley, et al. (2016). « A thrifty variant in CREBRF strongly influences body mass index in Samoans. » Nat Genet 48(9): 1049-1054.

Montagne, L., A. Raimondo, et al. (2014). « Identification of two novel loss-of-function SIM1 mutations in two overweight children with developmental delay. » Obesity (Silver Spring) 22(12): 2621-2624.

Morandi, A., D. Meyre, et al. (2012). « Estimation of newborn risk for child or adolescent obesity: lessons from longitudinal birth cohorts. » PLoS One 7(11): e49919.

Morassut, R. E., C. Tian, et al. (2020). « Identifying factors associated with obesity traits in undergraduate students: a scoping review. » Int J Public Health 65(7): 1193-1204.

Nano, J., M. Ghanbari, et al. (2017). « Epigenome-Wide Association Study Identifies Methylation Sites Associated With Liver Enzymes and Hepatic Steatosis. » Gastroenterology 153(4): 1096-1106 e1092.

Nead, K. T., A. Li, et al. (2015). « Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals. » Hum Mol Genet 24(12): 3582-3594.

Nikpay, M., P. Lau, et al. (2020). « SGCG rs679482 Associates With Weight Loss Success in Response to an Intensively Supervised Outpatient Program. » Diabetes 69(9): 2017-2026.

Paternoster, L., D. M. Evans, et al. (2011). « Genome-wide population-based association study of extremely overweight young adults–the GOYA study. » PLoS One 6(9): e24303.

Pearce, L. R., N. Atanassova, et al. (2013). « KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation. » Cell 155(4): 765-777.

Philippe, J., P. Stijnen, et al. (2015). « A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity. » Int J Obes (Lond) 39(2): 295-302.

Pigeyre, M., M. Saqlain, et al. (2018). « Obesity genetics: insights from the Pakistani population. » Obes Rev 19(3): 364-380.

Pigeyre, M., F. T. Yazdi, et al. (2016). « Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity. » Clin Sci (Lond) 130(12): 943-986.

Pooya, S., S. Blaise, et al. (2012). « Methyl donor deficiency impairs fatty acid oxidation through PGC-1alpha hypomethylation and decreased ER-alpha, ERR-alpha, and HNF-4alpha in the rat liver. » J Hepatol 57(2): 344-351.

Qasim, A., A. J. Mayhew, et al. (2019). « Gain-of-function variants in the melanocortin 4 receptor gene confer susceptibility to binge eating disorder in subjects with obesity: a systematic review and meta-analysis. » Obes Rev 20(1): 13-21.

Reddon, H., H. C. Gerstein, et al. (2016). « Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study. » Sci Rep 6: 18672.

Reddon, H., J. L. Gueant, et al. (2016). « The importance of gene-environment interactions in human obesity. » Clin Sci (Lond) 130(18): 1571-1597.

Retnakumar, S. V. and S. Muller (2019). « Pharmacological Autophagy Regulators as Therapeutic Agents for Inflammatory Bowel Diseases. » Trends Mol Med 25(6): 516-537.

Robiou-du-Pont, S., A. Bonnefond, et al. (2013). « Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population. » Int J Obes (Lond) 37(7): 980-985.

Robiou-du-Pont, S., L. Yengo, et al. (2013). « Common variants near BDNF and SH2B1 show nominal evidence of association with snacking behavior in European populations. » J Mol Med (Berl) 91(9): 1109-1115.

Romier, B., C. Ivaldi, et al. (2018). « Production of Elastin-Derived Peptides Contributes to the Development of Nonalcoholic Steatohepatitis. » Diabetes 67(8): 1604-1615.

Rouskas, K., A. Kouvatsi, et al. (2012). « Common variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 show evidence of association with adult obesity in the Greek population. » Obesity (Silver Spring) 20(2): 389-395.

Rouskas, K., D. Meyre, et al. (2012). « Loss-of-function mutations in MC4R are very rare in the Greek severely obese adult population. » Obesity (Silver Spring) 20(11): 2278-2282.

Saeed, S., T. A. Butt, et al. (2012). « High prevalence of leptin and melanocortin-4 receptor gene mutations in children with severe obesity from Pakistani consanguineous families. » Mol Genet Metab 106(1): 121-126.

Samaan, Z., S. S. Anand, et al. (2013). « The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression. » Mol Psychiatry 18(12): 1281-1286.

Samaan, Z., Y. K. Lee, et al. (2015). « Obesity genes and risk of major depressive disorder in a multiethnic population: a cross-sectional study. » J Clin Psychiatry 76(12): e1611-1618.

Sanchez, A., P. Rojas, et al. (2016). « Micronutrient Deficiencies in Morbidly Obese Women Prior to Bariatric Surgery. » Obes Surg 26(2): 361-368.

Scherag, A., C. Dina, et al. (2010). « Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. » PLoS Genet 6(4): e1000916.

Speliotes, E. K., C. J. Willer, et al. (2010). « Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. » Nat Genet 42(11): 937-948.

Stryjecki, C., A. Alyass, et al. (2018). « Ethnic and population differences in the genetic predisposition to human obesity. » Obes Rev 19(1): 62-80.

Stutzmann, F., S. Cauchi, et al. (2009). « Common genetic variation near MC4R is associated with eating behaviour patterns in European populations. » Int J Obes (Lond) 33(3): 373-378.

Stutzmann, F., K. Tan, et al. (2008). « Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees. » Diabetes 57(9): 2511-2518.

Stutzmann, F., V. Vatin, et al. (2007). « Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene. » Hum Mol Genet 16(15): 1837-1844.

Talukdar, S., D. Y. Oh, et al. (2012). « Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. » Nat Med 18(9): 1407-1412.

Tam, V., N. Patel, et al. (2019). « Benefits and limitations of genome-wide association studies. » Nat Rev Genet 20(8): 467-484.

Tam, V., M. Turcotte, et al. (2019). « Established and emerging strategies to crack the genetic code of obesity. » Obes Rev 20(2): 212-240.

Tremaroli, V. and F. Backhed (2012). « Functional interactions between the gut microbiota and host metabolism. » Nature 489(7415): 242-249.

Trier, C., M. Hollensted, et al. (2021). « Obesity treatment effect in Danish children and adolescents carrying Melanocortin-4 Receptor mutations. » Int J Obes (Lond) 45(1): 66-76.

Turcotte, M., A. Abadi, et al. (2019). « Genetic contribution to waist-to-hip ratio in Mexican children and adolescents based on 12 loci validated in European adults. » Int J Obes (Lond) 43(1): 13-22.

Vashi, N., C. Stryjecki, et al. (2016). « Genetic markers of inflammation may not contribute to metabolic traits in Mexican children. » PeerJ 4: e2090.

Vaxillaire, M., J. Veslot, et al. (2008). « Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study. » Diabetes 57(1): 244-254.

Vazquez-Moreno, M., D. Locia-Morales, et al. (2020). « Causal Association of Haptoglobin With Obesity in Mexican Children: A Mendelian Randomization Study. » J Clin Endocrinol Metab 105(7).

Vazquez-Moreno, M., D. Locia-Morales, et al. (2021). « The MC4R p.Ile269Asn mutation confers a high risk for type 2 diabetes in the Mexican population via obesity dependent and independent effects. » Sci Rep 11(1): 3097.

Vazquez-Moreno, M., A. Perez-Herrera, et al. (2021). « Association of gut microbiome with fasting triglycerides, fasting insulin and obesity status in Mexican children. » Pediatr Obes 16(5): e12748.

Vazquez-Moreno, M., H. Zeng, et al. (2020). « The Melanocortin 4 Receptor p.Ile269Asn Mutation Is Associated with Childhood and Adult Obesity in Mexicans. » J Clin Endocrinol Metab 105(4).

Vogelezang, S., J. P. Bradfield, et al. (2020). « Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. » PLoS Genet 16(10): e1008718.

Wahart, A., T. Hocine, et al. (2019). « Role of elastin peptides and elastin receptor complex in metabolic and cardiovascular diseases. » FEBS J 286(15): 2980-2993.

Walters, R. G., S. Jacquemont, et al. (2010). « A new highly penetrant form of obesity due to deletions on chromosome 16p11.2. » Nature 463(7281): 671-675.

Wermter, A. K., A. Scherag, et al. (2008). « Preferential reciprocal transfer of paternal/maternal DLK1 alleles to obese children: first evidence of polar overdominance in humans. » Eur J Hum Genet 16(9): 1126-1134.

Yang, Y., A. A. van der Klaauw, et al. (2019). « Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis. » Nat Commun 10(1): 1718.

Yazdi, F. T., S. M. Clee, et al. (2015). « Obesity genetics in mouse and human: back and forth, and back again. » PeerJ 3: e856.

Zimmer, R., H. R. Scherbarth, et al. (2013). « Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial. » Ann Rheum Dis 72(11): 1830-1835.